Nearly 32 years ago, Jeana Nesmith Russell was beginning her dream career as a nurse in one of the University of Alabama at Birmingham’s hospital units while pursuing her graduate degree. Little did she know that her life was about to change forever.

“Life over limb” is not a phrase Amanda Pullen-Hendrix ever thought she would hear, especially not on her 29th birthday. But on July 12, 2020, what she at first believed was an asthma attack turned out to be a life-threatening stroke and multiple blood clots.

For patients with the life-threatening genetic respiratory disorder known as cystic fibrosis (CF), daily treatment routines often mean a life of inconvenience and discomfort. For UAB Medicine patient Mark Sleeper, however, CF is no longer a matter of constant care. Major advances in drug therapy at the UAB Gregory Fleming James Cystic Fibrosis Research Center gave Sleeper what he calls “a completely normal life.”