Cystic Fibrosis

Cystic fibrosis (CF) primarily affects the lungs and digestive system, but breathing problems cause the most serious issues for those suffering from the disease. This life-threatening, inherited (genetic) condition causes thick mucus to build up in the body’s organs, especially the lungs and pancreas. The cells responsible for producing mucus, sweat, and digestive juices change those bodily fluids from thin, slippery secretions to ones that are thick and sticky. As a result, the lungs become clogged with mucus, making it difficult to breathe. Bacteria also can get trapped in the lungs, causing serious infections. In the pancreas, the mucus interferes with the organ’s normal function of helping the body digest food.

UAB Medicine is a global leader in CF clinical care and research, making us a unique resource for patients in Alabama. The UAB Adult CF Center is a multi-specialty clinic staffed by a wide range of medical professionals, including a dietitian, a social worker, an endocrinologist, four pulmonologists, a pharmacist, a physical therapist, two nurse coordinators, and two advanced practice providers, or APPs. Theis team also works closely with many other medical and surgical specialists with expertise in the unique issues that people with CF face, and it can address the full range of needs for adult patients with CF.

UAB Medicine is home to the state’s only accredited Cystic Fibrosis Center, as designated by the Cystic Fibrosis Foundation, and we Participate in the Cystic Fibrosis Foundation’s Therapeutics Development Network (TDN). As one of only a handful of research centers funded by the foundation, we may be able to offer our patients the latest and most advanced CF treatments, many of which are not available at other medical centers.

The UAB Adult CF Center has grown significantly and now cares for over 300 patients across nine states. It is a national leader in clinical research trials that have led to important new therapies. In 2022, the UAB Adult CF Center received full re-accreditation by the Cystic Fibrosis Foundation, and in 2023 it was awarded its Quality Care Award for effective processes and seeking to include patients’ voices in improving care.


The UAB Adult CF Center is currently accepting new patients. To make an appointment, please have your referring physician’s office call UAB Pulmonary Scheduling at 205-801-7545, or call 205-996-LUNG (5864). Our schedulers will ask for demographic and insurance information, then they can schedule your appointment. Once the appointment is made, the referring office should fax your records to 205-975-2440. If you have any questions, please call us at 205-975-0763.

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