Cold Knife Conization

Cold knife conization (CKC) is a procedure used to remove tissue from a woman’s cervix, the entrance to the womb (uterus). It is most often used as a treatment for precancerous changes but may also help to diagnose abnormal cells. CKC is usually performed after a test called colposcopy has identified abnormal cells, including precancerous changes (dysplasia).  

CKC is the removal of a cone-shaped piece of tissue containing abnormal cells, which is often the only treatment needed for precancerous changes in the cervix. Cold knife conization allows the surgeon to take a larger amount of tissue than biopsies performed as part of a colposcopy.

The tissue removed is examined under a microscope for signs of disease. If all abnormal cells are not fully removed or if invasive cancer is found, additional treatment is required.

CKC is performed under regional or general anesthesia. The duration of the procedure may vary depending on the surgeon’s findings, but it often takes less than one hour. Patients often return to work the following day, although they will experience some cramping and bleeding. Patients will be advised to avoid heavy lifting and sexual intercourse during the few weeks after CKC.

Why choose UAB Medicine

UAB Obstetrics and Gynecology offers complete women’s health care, delivered by physicians and nurses dedicated to excellence. Our physicians are nationally recognized specialists in their fields, so you can rest assured that you are receiving the most advanced care available. Our program is consistently ranked among the best of its kind in the country by U.S. News & World Report.

As part of the UAB Division of Women’s Reproductive Healthcare, UAB Obstetrics and Gynecology’s services range from complete obstetric care to the medical and surgical treatment of complex gynecological concerns. Because UAB Medicine is a major center for research, patients may have access to promising new techniques and treatments not available at other medical centers. Our physicians are here for you at every stage of life, from your first gynecological exam to delivering your baby and helping guide you through menopause.

Videos

Resources

• Cold Knife Conization Procedure Guide
• UAB Department of Obstetrics and Gynecology
• National Institutes of Health