MD Learning Channel - Nephrology

Blood-group compatibility and histocompatibility must be determined prior to transplant. With a positive cross-match precluding transplantation, transplant nephrologist, Vineeta Kumar MD, explains how these matches are determined and how technology can be used to rectify this incompatible transplant.

About 35% of patients that come forward with living donors will be found to be blood-group incompatible, and another 11% are found to be tissue-incompatible with their potential living donor. Transplant surgeon, Jayme Locke MD, discusses solutions such as desensitation for this large patient population.