Program for Personalized Prostate Cancer Care

Prostate cancer is one of the deadliest cancers among men. More than 265,000 new cases will be diagnosed in the United States in 2022, and over 34,000 men will die from the disease, according to the American Urological Association. The UAB Program for Personalized Prostate Cancer Care seeks to lower those numbers by combining the latest advances in screening and treatment.

The program starts with a highly personalized evaluation of each patient, followed by screening tests that can include:

  • Prostate-specific antigen (PSA) testing, a special type of blood test
  • Advanced serum and urine biomarker testing, which goes beyond the PSA blood test
  • An MRI/US fusion-guided prostate biopsy, which combines magnetic resonance imaging (MRI) and ultrasound (US) technologies

The MRI/US fusion-guided technique allows for a “targeted biopsy,” which focuses directly on suspicious areas of the prostate in collecting samples for testing. It is one of the greatest advancements in prostate cancer in over 30 years, because the cancer can be detected earlier, and it also helps physicians better understand the disease and allows patients to make more informed decisions about their care.

The program also offers the latest treatment options, including improved “whole-gland” therapies that enable more precise radiation targeting, and a wider range of minimally invasive surgical approaches, which require only one or a few small incisions (cuts). Also, new treatments are available for cases of prostate cancer that are detected very early and only affect one area of the prostate. These include various types of “focal therapy”, in which segments of the prostate gland are destroyed using either needles or heat that is generated with ultrasound energy, thereby precisely targeting cancerous areas in the prostate.


UAB Medicine was the first medical center in Alabama and among the first in the southeast to offer the MRI/US fusion-guided prostate biopsy technique. Our urologists are regional and national leaders in their field, partnering as a team with our medical oncologists and radiation oncology specialists to sensitively diagnose and treat prostate cancer in the most efficient and caring way possible. Patients receive personalized care plans that include the latest treatment technology and minimize the effects on urinary continence and sexual health.

When prostate surgery is necessary, UAB’s experienced urologic surgeons have access to robotic surgery technology, which reduces patient discomfort and shortens recovery time. UAB was a pioneer in using robotic surgery and now offers the most advanced “single-port” robotic platform, which requires only one incision. Also, the Program for Personalized Prostate Cancer Care is part of the O’Neal Comprehensive Cancer Center at UAB, which is the only Comprehensive Cancer Center in a six-state region. This means that patients benefit from UAB’s extensive research efforts, including clinical trials that often provide access to promising new treatments long before they are available at other medical centers.






UAB is an active participant in research and clinical trials. We encourage you to speak to your physician about research and clinical trial options and browse the link below for more information.

View Clinical Trials