The Mitraclip Percutaneous Mitral Valve Repair System is a minimally invasive procedure to treat mitral regurgitation, the most common type of heart valve insufficiency. The mitral valve controls normal blood flow from the left atrium to the left ventricle, two of the heart’s four large chambers. When the mitral valve doesn't close fully, blood flows backward into the upper heart chamber (left atrium) from the lower chamber as it contracts. This leads to a decrease in blood flow to the rest of the body, which may cause the heart to try to pump harder and result in congestive heart failure. Its incidence tends to become even more prevalent as the population ages, making new, less invasive treatment options welcome alternatives for a growing number of patients.

MitraClip is a cardiac catheterization procedure performed with the patient under general anesthesia. The MitraClip device is introduced through the femoral vein and advanced to the left atrium to position the clip above the mitral valve and guide it into the left ventricle of the heart. When retracted, the clip grasps the sides of the existing valves (known as leaflets) and closes them to create an edge-to-edge repair that stops the regurgitation and helps the heart pump blood more effectively. Although the effectiveness and durability of this repair typically are not as good as with surgical valve reconstruction, the MitraClip procedure offers a new therapeutic option to patients who are denied surgery because of their advanced age or other risk factors, and it is the only FDA-approved alternative to valve reconstruction surgery.


With the first and largest comprehensive heart valve program in the state, UAB Medicine provides continuing care for patients who have or are at risk for valve disease. Our team of surgeons and cardiologists are among the nation’s most highly regarded physicians, and they provide a multidisciplinary approach to the diagnosis and treatment of valve disease. From aortic valve stenosis to mitral valve regurgitation, and from traditional open-heart surgery to the latest in minimally invasive procedures and robotic-assisted valve repair surgery, UAB patients benefit from our expertise in treating patients with valve disease.

The UAB Comprehensive Valve Program has built an impressive list of accomplishments in recent years. Our cardiologists and heart surgeons performed the first transcatheter aortic valve replacement (TAVR) in Alabama; to date UAB has performed more TAVRs than any other hospital in the state. As an added service, patients who have been told by non-UAB doctors that they need valve surgery can speak to a UAB valve surgeon for a second opinion.






UAB is an active participant in research and clinical trials. We encourage you to speak to your physician about research and clinical trial options and browse the link below for more information.

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