Melanoma Treatment with Radioactive Plaques

Melanoma treatment with radioactive plaques is a radiation therapy for cancer of the eye. Melanoma is the most common type of eye tumor in adults. Chroidal melanoma is the most common of the intraocular tumors. The chroid is the layer of blood vessels and connective tissue between the white of the eye (sclera) and the retina that provides nutrition to the inner eye areas. Radioactive plaque is one option doctors have to treat such tumors. Plaque brachytherapy is the most frequently used eye-sparing treatment for choroidal melanoma. The radioactivity usually comes from use of cesium or Iodine-125. Brachytherapy is an accepted treatment for this melanoma of the eye.  Brachytherapy is a form of radiation therapy that attacks malignant tumors by placing a radioactive source near the tumor. The surgery is performed under general anesthesia in children and local anesthesia in adults. The patient stays in the hospital under strict radiation safety precautions for the duration of the radiation exposure, after which the plaque is removed. The surgery for plaque removal is a short, simple procedure and often the patient can go home later the same day. The effects are periodically assessed every 6 weeks to 3 months until there is complete regression. 


UAB Ophthalmology has more than 25 physicians, many of them named among the top doctors in their fields nationally. They are renowned for their advances in eye care, breaking through old ways of treating blinding eye diseases and revolutionizing many areas of ophthalmology.

Ophthalmology care at UAB is located in UAB Callahan Eye Hospital, one of the busiest eye hospitals in the country, where specialists work together to treat complex cases. The UAB Callahan Eye Hospital surgical suite houses nine operating rooms dedicated to eye surgery as well as a 24/7 Eye emergency room, which is the region’s only Level I Ocular Trauma Center. More than 11,000 surgeries are performed at UAB Callahan Eye Hospital each year, and we conduct more reconstructive eye surgeries than any other facility in the world. Patients come from around the nation to be treated for eye conditions at UAB.

The UAB Center for Low Vision Rehabilitation works with patients to maximize vision and provides services such as orientation and mobility, occupational therapy, and support groups for patients dealing with vision loss or impairment.

Through ongoing research and clinical trials, UAB continues to make great strides in the field of ophthalmology. In addition to our physicians, we have a team of vision scientists who are fully dedicated to researching causes, preventions, and cures for eye diseases such as diabetic retinopathy, glaucoma, and macular degeneration. Many UAB ophthalmologists have received funding from prestigious research organizations and institutions and collaborate in clinical care to deliver the latest in scientific discovery to our patients.








UAB is an active participant in research and clinical trials for Melanoma Treatment with Radioactive Plaques. We encourage you to speak to your physician about research and clinical trial options and browse the link below for more information on clinical trials at

View Clinical Trials