Donor Egg In Vitro Fertilization

Donor egg in vitro fertilization  (IVF) is an option for women who cannot use their own eggs in an IVF cycle. Thousands of successful donor egg cycles have been conducted throughout the world, and there is no increase in birth defects or other fetal abnormalities with this pregnancy method. Egg donors can be either known or unknown to the patient and are usually aged in their twenties or early thirties. A known donor can be a friend or relative, while unknown donors are those anonymously chosen from the UAB donor egg pool. Patients undergoing donor egg IVF are administered medications to synchronize their cycle with that of the donor's. The donor undergoes ovulation induction with injectable gonadotropins until her eggs mature and are ready for retrieval. Then the donor eggs are combined with the patient's partner's sperm and placed in incubators for three days. Once mature, the embryos are transferred to the patient's uterus. The number of embryos transferred depends upon many variables. Additional embryos can be frozen for use in future cycles. Prior to embryo implantation, the patient will have received hormones, such as progesterone and estrogen, to mimic the normal pregnancy process. 


UAB Medicine’s nationally recognized physicians have years of experience in diagnosing and treating both male and female infertility. We treat infertility with a team approach that includes a urologist, a reproductive endocrinologist, specialized nurses, and laboratory scientists. A variety of conventional treatments are available, including corrective microsurgery. For those who do not have a condition that can be treated, procedures such as intrauterine insemination or in vitro fertilization (IVF) may be used to help a couple get pregnant. Our fertility experts will determine a treatment plan that is best suited for each individual man and his partner. As a major center for research, UAB Medicine continues to investigate new advances in fertility treatment aimed at increasing the chances of conceiving healthy babies.





UAB is an active participant in research and clinical trials for Donor Egg In Vitro Fertilization. We encourage you to speak to your physician about research and clinical trial options and browse the link below for more information on clinical trials at

View Clinical Trials