Marfan Syndrome
Marfan syndrome is a medical condition that affects connective tissue, which holds the body’s cells, organs, and tissue together and helps the body grow and develop properly. It is a genetic disorder, meaning that it originates in the genes that are passed down from parents to children. Marfan syndrome can also occur even when caused by the parents’ genes. Connective tissue is found throughout the body, so Marfan syndrome can cause problems in many different parts of the body, including the heart, blood vessels, bones, joints, and eyes. The lungs, skin, and nervous system also may be affected. Some problems caused by Marfan syndrome, such as aortic enlargement (expansion of the main vessel that carries blood away from the heart to the rest of the body), can be life-threatening. Symptoms of Marfan syndrome may not appear until adulthood and can get worse over time. Some estimates suggest that half of the people with Marfan syndrome don’t know they have it. Treatment is available and is more effective the earlier the condition is detected and treated.
Why UAB
The UAB Congenital Heart Disease Program offers the most advanced care for structural heart disease, which often requires lifetime monitoring and care. Our multidisciplinary team of pediatric and adult cardiologists, cardiovascular surgeons, cardiovascular anesthesiologists, and maternal/fetal medicine specialists are uniquely qualified to treat patients before birth and into adulthood. In addition to seeing patients at the UAB Women & Infants Center and The Kirklin Clinic of UAB Hospital, UAB Medicine’s congenital heart disease specialists also see patients at North Alabama Children's Specialists in Huntsville and Physicians to Children/Central Alabama Children's Specialists in Montgomery.
Our modern ultrasound equipment allows many heart defects to be diagnosed before a child is born. Screening exams performed at 18-20 weeks are recommended for expectant mothers (or fathers) known to have congenital heart disease. If a defect is discovered, prenatal treatment and planning for delivery and postnatal treatment can be undertaken.
Thanks to advances in pediatric congenital care, the life expectancy for most patients now reaches far into adulthood, but more than 60% stop seeing a cardiologist once they turn 18. UAB’s Alabama Adult Congenital Heart Disease Program is designed to prevent that gap in care. As the only adult congenital heart disease program in the state and one of only a handful in the country, our expertise greatly increases the chances that symptoms will be identified early. This helps ensure that smaller problems are addressed before they develop into larger, more life-threatening issues such as heart failure, arrhythmia, residual congenital heart defects, endocarditis, and stroke.
Images and Videos
Dr. Cribbs on Business Break
More than 20,000 adults enter the Adult Congenital Heart Disease population every year, but 60% are lost to follow-up care.
Care of Adults with Congenital Heart Disease
Minimally Invasive Surgery for Valve Replacement
Dylan Fields was born with a congenital heart defect which led him to develop an enlarged right ventricle as a teenager. Pulmonary valve replacement was required. However, open heart surgery was avoided. Instead, UAB pediatric cardiologists replaced the valve using a minimally invasive procedure.
Fetal Cardiac Services at UAB Medicine
Drs. Joseph R. Biggio and Robb L. Romp discuss how the UAB Fetal Diagnosis and Care Center brings together experts at UAB Medicine and Children's of Alabama Joseph S. Bruno Pediatric Heart Center to care for high risk moms and babies from the moment a congenital abnormality is suspected.
Individuals born with congenital heart disease are now thriving into adulthood, but need lifelong follow-up care from sub-specialty experts.
Adult Congenital Heart Disease Risk Factors, Symptoms & Treatments
Some people are born with a defect or malformation in their heart or blood vessels, and this is called Congenital Heart Disease. UAB Cardiologist Edward Colvin, MD, talks to Daytime Alabama on WVTM-TV, Channel 13, in Birmingham, Ala., about the types of congenital heart disease and what adults with this disease should look for when choosing a doctor.


Related Conditions
Listed below are some conditions that may be related to or share some similarities with the condition addressed on this page.
CLINICAL TRIALS
UAB is an active participant in research and clinical trials for the diagnosis and treatment of male infertility. We encourage you to speak to your physician about research and clinical trial options and browse the link below for more information.
View Clinical TrialsMore from UAB
Around the Web
achaheart.org
nih.gov
Congenital Heart Defects
heart.org
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UPCOMING CLASSES AND EVENTS
- Genome: Unlocking Life's Code
Do you have your mother’s dimples? Or your father’s hairline? What makes us, us? And how much of it actually sets us apart from every other living thing on Earth?
Genome: Unlocking Life’s Code begins to unravel the mystery behind the complete set of instructions needed for every living thing on Earth to grow and function: the genome. Discover how your genome could be the key to maximizing your future quality of life as genomic science helps open the way to more personalized healthcare. See yourself in a new way: as an individual, as a member of a family, and as part of the diversity of life on Earth.
Genome: Unlocking Life’s Code opens January 19 at McWane Science Center and was made possible in part by financial support secured by the Foundation for the National Institutes of Health. The exhibit is sponsored by UAB Medicine, which is using its knowledge of the human genome to advance the field of precision medicine, an exciting approach to health care that combines the absolute latest in the prediction and prevention, diagnosis, and treatment of disease to deliver truly individualized patient care.