Hereditary Breast Cancer Ovarian Syndrome

Hereditary breast ovarian cancer syndrome (BRCA1/BRCA2) is an inherited tendency to develop breast, ovarian and other cancers. Most cancers are not inherited, but with hereditary breast ovarian cancer (HBOC), the cancer risk is passed from generation to generation in a family. Two genes are associated with developing this condition: BRCA1 and BRCA2  (stands for BReast CAncer). Mutations in these genes give a woman an increased lifetime risk of developing breast and ovarian cancers. Men who have this gene mutation have an increased risk of breast cancer and prostate cancer. Doctors often point to hereditary breast ovarian cancer when there are multiple cases of breast and/or ovarian cancer among blood relatives.  


The UAB Medicine cancer program is ranked among the best in the nation. Patients who come to UAB Medicine for breast cancer treatment have access to the full array of specialists within our system, including medical, surgical, and radiation oncologists, certified oncology nurses, nurse navigators, reconstructive surgeons, and more.

UAB Medicine's Breast Health Center is unique in that we deliver the full range of breast health services including screening, diagnosis, treatment, rehabilitation, and research. Through our Lynne Cohen Preventive Care Program for Women's Cancer, we also offer comprehensive risk assessments and prevention strategies for breast, ovarian, and uterine cancer, arming women with knowledge to make informed decisions about their cancer risk and care. For women whose cancer is now in remission, our Breast Cancer Survivorship Clinic provides the ongoing medical and emotional support they need to remain healthy long after their treatment has come to an end.

As a part of the O'Neal Comprehensive Cancer Center at UAB, our innovative Interdisciplinary Breast Cancer Clinic utilizes a team of dedicated breast specialists to help patients evaluate their options as effectively as possible, which also allows patients and their families to meet with our various team members in one convenient visit. This approach facilitates better communication among team members, patients, and their families. Each patient is evaluated initially by one of our breast specialists before meeting face to face with other team members to discuss long-term treatment planning. Individualized care plans are developed in roundtable discussions and discussed with the patient and family members during the same visit, which allows questions to be asked of each team member.

The UAB Integrative Medicine Clinic features a collaborative approach to patient care among multiple practitioners and utilizes therapies that are proven in both traditional and complementary health care. Integrative medicine combines traditional medical care with programs designed to address the physical, biological, lifestyle, emotional, psychological, and spiritual aspects of health and illness. It focuses on the whole person, including family members, to optimize wellness and manage the challenges throughout each patient’s chronic disease or cancer care journey, from prevention to survivorship and beyond. It encourages the human capacity for healing and emphasizes the relationship between practitioner and patient.








UAB is an active participant in research and clinical trials for the diagnosis and treatment of hereditary breast ovarian cancer sydrome. We encourage you to speak to your physician about research and clinical trial options and browse the link below for more information.

View Clinical Trials