Structural Heart & Valve Disease

Heart valve disease is a condition in which one or more heart valves don't work as they should. Valve problems may be present at birth or may be caused by infections, heart disease or heart attacks. The heart has four valves. Each valve has flaps of tissue that open and close with every heartbeat. The flaps make sure the blood flows in the right direction. One or more valves may not open fully or let blood leak back into the heart chambers, making the heart work harder and affect its ability to pump blood. Most heart valve problems have no symptoms and do not cause problems, but treatment is necessary in some cases.


With the first and largest comprehensive heart valve program in the state, UAB Medicine provides continuing care for patients who have or are at risk for valve disease. Our team of surgeons and cardiologists are among the nation’s most highly regarded physicians, and they provide a multidisciplinary approach to the diagnosis and treatment of valve disease. From aortic valve stenosis to mitral valve regurgitation, and from traditional open-heart surgery to the latest in minimally invasive procedures and robotic-assisted valve repair surgery, UAB patients benefit from our expertise in treating patients with valve disease.

The UAB Comprehensive Valve Program has built an impressive list of accomplishments in recent years. Our cardiologists and heart surgeons performed the first transcatheter aortic valve replacement (TAVR) in Alabama; to date UAB has performed more TAVRs than any other hospital in the state. As an added service, patients who have been told by non-UAB doctors that they need valve surgery can speak to a UAB valve surgeon for a second opinion.

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Related Conditions

Listed below are some conditions that may be related to or share some similarities with the condition addressed on this page.


UAB is an active participant in research and clinical trials for the diagnosis and treatment of heart valve disease. We encourage you to speak to your physician about research and clinical trial options and browse the link below for more information on clinical trials at

View Clinical Trials