Cutaneous T-Cell Lymphoma

Cutaneous T-cell lymphoma is a rare cancer caused when infection-fighting white blood cells become malignant and attack the skin. This results in rashes and, sometimes, tumors, which can be mistaken for other dermatological conditions. Cutaneous T-cell lymphoma typically is a slow-progressing cancer that develops over a number of years. It is one of a group of disorders known as non-Hodgkin lymphoma, all of which affect the lymphatic system. This is part of the immune system, which protects the body against infection and disease. The two most common types of cutaneous T-cell lymphoma are mycosis fungoides and the Sezary syndrome. If not treated, the cancer can move into the lymph nodes and to other parts of the body, such as the liver or spleen.


UAB Medicine recently launched a dedicated Lymphoma Program within the O'Neal Comprehensive Cancer Center at UAB to merge the expertise of a variety of specialists. A joint effort between the Department of Hematology/Oncology and the Department of Medicine, the lymphoma program offers the absolute latest in medical technology for treating and screening for the various kinds of lymphoma. The program also actively participates in clinical trials of promising new lymphoma treatments, including some that are not available at other medical centers.

The Lymphoma Program’s interdisciplinary team includes nationally known physicians who are experts in hematology, medical oncology, bone marrow transplant, hematopathology, radiation oncology, integrative medicine, surgical oncology, and survivorship. The program’s research team is dedicated to improving treatments and finding a cure for Hodgkin and non-Hodgkin lymphoma and other blood disorders and cancers in adults, including myelodysplastic syndromes (MDS), which are a group of disorders that prevent bone marrow from producing enough healthy blood cells.

Because UAB is a member of the National Comprehensive Cancer Network (NCCN), we are involved in the development of national practice guidelines for lymphoma treatment. We are a regional center of excellence, and thanks to our active research program, we often can help patients enroll in clinical trials. Some of these treatments may even be offered at our convenient neighborhood health center on Acton Road off I-459. UAB also offers a broad array of supplemental resources for lymphoma patients, including the Supportive Care and Survivorship Clinic.






UAB is an active participant in research and clinical trials for cutaneous t-cel lymphoma. We encourage you to speak to your physician about research and clinical trial options and browse the link below for more information.

View Clinical Trials