Cardiac Sarcoma

Cardiac sarcoma is a rare cancer that develops in the soft tissue of the heart. While more than 75 percent of primary tumors of the heart are benign, a cardiac sarcoma is usually malignant. Tumors of the heart may develop on the surface of the heart, in one of the chambers, or within the muscle tissue. The most common type of cardiac sarcoma is angiosarcoma, which usually begins in the upper right chamber or on the outer surface of the heart. About 25 percent of angiosarcomas develop inside the heart and eventually can restrict blood flow and cause symptoms such as swelling of the legs, feet, ankles, and abdomen. Patients may experience fatigue, shortness of breath, or heart palpitations, all of which can be symptoms of other heart-related issues.


At UAB, you will receive expert, personalized care from our cardiology clinics both on campus and at our suburban center at Acton Road just off I-459. Specialists from UAB’s world-renowned team of cardiologists offer you the best evidence-based care for coronary artery disease, congestive heart failure, rhythm disturbances, diseased valves, and other heart and vessel conditions. And when you visit our clinics, you can expect friendly, personalized care backed by UAB’s sophisticated facilities and equipment.

If you require pacemakers, surgery, or other advanced treatments, you will receive a timely referral to our sub-specialty colleagues at The Kirklin Clinic of UAB Hospital in the city’s Medical Center District.






UAB is an active participant in research and clinical trials for the diagnosis and treatment of cardiac sarcoma. We encourage you to speak to your physician about research and clinical trial options and browse the link below for more information on clinical trials at

View Clinical Trials