Bioprosthetic Valve Stenosis

Bioprosthetic valve stenosis is a condition that in some cases necessitates the use of prosthetic tissue valves to replace the native aortic, mitral, tricuspid or pulmonic valves when they stop competently functioning. These valves are made from pig or cow tissue and typically have a lifespan of 10-15 years. In cases where these tissue valves begin failing and stop working well, surgical valve re-replacement surgery may be indicated. Some patients are not candidates for surgical valve re-replacement surgery based on their age and other complications, and in such cases a transcatheter valve-in-valve procedure may be performed.


With the first and largest comprehensive heart valve program in the state, UAB Medicine provides continuing care for patients who have or are at risk for valve disease. Our team of surgeons and cardiologists are among the nation’s most highly regarded physicians, and they provide a multidisciplinary approach to the diagnosis and treatment of valve disease. From aortic valve stenosis to mitral valve regurgitation, and from traditional open-heart surgery to the latest in minimally invasive procedures and robotic-assisted valve repair surgery, UAB patients benefit from our expertise in treating patients with valve disease.

The UAB Comprehensive Valve Program has built an impressive list of accomplishments in recent years. Our cardiologists and heart surgeons performed the first transcatheter aortic valve replacement (TAVR) in Alabama; to date UAB has performed more TAVRs than any other hospital in the state. As an added service, patients who have been told by non-UAB doctors that they need valve surgery can speak to a UAB valve surgeon for a second opinion.

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Related Conditions

This procedure may be used to treat or diagnose several different conditions. We have listed some of these conditions below for your convenience. Please note that this is not a comprehensive list and may vary depending on your specific diagnosis.


UAB is an active participant in research and clinical trials for the diagnosis and treatment of bioprosthetic valve stenosis. We encourage you to speak to your physician about research and clinical trial options and browse the link below for more information on clinical trials at

View Clinical Trials