UAB Medicine News


New Options for Residency in Ophthalmology Open for Young Researchers

The UAB Department of Ophthalmology is enhancing its residency program with a new track, giving incoming residents the option to participate in an in-depth clinical or basic research project of their choice.

Both the traditional clinical path and the more research-intensive academic path provide training in research methodology, but residents who choose the academic path will have protected research time during their second year, allowing them to complete an 18-month research project.

In the first year of the program, residents on both tracks complete a one-year project focusing on background, current state of knowledge, and a clinically relevant research component.

In the second year, academic-path residents will begin an 18-month research project. This provides more intensive research experience than previously possible. Projects will culminate with presentations at the department’s symposium during their third year.

“The first group of academic path residents will set the stage for those that follow,” says Russell Read, MD, the Max and Lorayne Cooper Professor for Ophthalmology Residency Training director. “We were very fortunate that in the first year we offered this research track, we had three of our five first-year residents express interest and choose to follow the track.”

The First Class

The department recently saw its first three residents complete the research-intensive program: Jack Parker Jr., MD, Pooja Godara, MD, and David Neely, MD.

Each resident partnered with a research faculty mentor to develop a project that resulted in multiple presentations and manuscripts.

Dr. Parker’s research focused on a new surgical option for patients with advanced keratoconus called Bowman layer transplantation. Keratoconus is a progressive eye disease in which the normally round cornea thins and begins to bulge into a cone-like shape. This cone shape deflects light as it enters the eye on its way to the light-sensitive retina, causing distorted vision.

The use of Bowman layer transplantation could be a way to halt progressive advanced keratoconus.

“Bowman layer fragmentation is one of the earliest and most significant changes in keratoconus,” Parker says. “Perhaps by replacing the Bowman layer, we can mechanically bolster and shore up the cornea, protecting it from further progression.”

Pooja Godara, MD, researched the measurement of ocular perfusion pressure in nonhuman studies via continuous radio telemetry, and what that means for the study of glaucoma. Ocular perfusion pressure is the pressure at which blood enters the eye. Glaucoma is the second leading cause of blindness worldwide, with more than 50 million people affected, according to the World Health Organization.

“Glaucoma is conceivably a disease of multiple pressures, more than just intraocular pressure,” Godara says.

Dr. Neely’s research assessed a link between subretinal drusenoid deposits (SDD) and age-related macular degeneration (AMD). To determine whether SDD in eyes in normal macular health increases risk for early AMD, this study examined the association between the presence of SDD at baseline in a cohort of older adults in normal macular health and incident of AMD three years later.

Results suggest that SDD in older eyes with normal macular health is a risk factor for the development of early AMD. Older adults in seemingly normal macular health yet having SDD may warrant closer clinical monitoring for the possible onset of early AMD.

Next Steps for the Program

Dr. Read says he expects one resident per year on average to select the research track, as it is a demanding curriculum for residents still responsible for clinical activities, call, lecture and conference attendance.

The research track offers the residents five weeks of dedicated block time during their second year to conduct the bulk of their research data gathering.

“These residents are experiencing firsthand, and early on, the realities of life as a clinician-scientist,” he says. “They learn how to balance clinical responsibilities and demands with those of their research program.”

Read says the program is important because it teaches the residents clinically relevant issues that require additional understanding and knowledge required to reduce or alleviate human suffering.

“The UAB Ophthalmology Residency program is already a top-tier clinical training program,” Read says. “This new option gives our residents the opportunity to continue to make a difference in patients’ lives one at a time via excellent clinical care, but also to add to our ophthalmologic knowledge base, enhancing the practice of all ophthalmologists — which is a huge force multiplier in our battle against blinding diseases.”

The hope for this program, Read says, is to light the fire of scientific inquiry in those who participate so that they go on to make the important discoveries needed to improve the care of patients.

“At the least, we expect that participation in the research track will enlighten them to the processes involved in research so they have a fuller understanding and are able to read the scientific literature with an informed, critical eye. That will make them better ophthalmologists and lifelong learners.”

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