UAB Medicine

Total Skin Irradiation

Total Skin Irradiation (TSI), and also referred to as Total Skin Electron Irradiation (TSEI) or Total Skin Electron Beam (TSEB), is an External Beam Radiotherapy (EBRT). This treatment therapy uses electrons directed at the entire surface of the body. The radiation penetrates the outer layers of the skin, but does not go deeper into tissues and organs below the skin. It is often used to treat cutaneous T-cell lymphoma. If detected early, it can result in the disappearance of any signs or symptoms of the disease.

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